If your patient shared their results with you electronically, you can download a provider. The Know:BRCA Assessment uses the BRCAPRO model and software.
Breast Cancer Risk Prediction Models The information on this page is archived and provided for reference purposes only. • • • • The following risk prediction models are intended primarily for research use and have been peer-reviewed, meaning the methodology and results of these models have been evaluated by qualified scientists and clinicians and published in scientific and medical journals. Absolute Risk Prediction Models Absolute cancer risk is the probability that an individual with given risk factors and a given age will develop cancer over a defined period of time. Examples of these risk factors include race, age, sex, genetics, body mass index, family history of cancer, history of tobacco use, use of aspirin and nonsteroidal anti-inflammatory drugs (NSAIDS), physical activity, use of hormone replacement therapy, reproductive factors, history of cancer screening, and dietary factors. Developing statistical models that estimate the probability of developing cancer over a defined period of time will help clinicians identify individuals at higher risk of specific cancers, allowing for earlier or more frequent screening and counseling of behavioral changes to decrease risk. These types of models also will be useful for designing future chemoprevention and screening intervention trials in individuals at high risk of specific cancers in the general population.
Models with Associated Websites • Matsuno RK, Costantino JP, Ziegler RG, et al. J Natl Cancer Inst.
Jun 22 2011;103(12):951-961. • • Gail MH, Costantino JP, Pee D, Bondy M, Newman L, Selvan M, Anderson GL, Malone KE, Marchbanks PA, McCaskill-Stevens W, Norman SA, Simon MS, Spirtas R, Ursin G, Bernstein L.
J Natl Cancer Inst. 2007 Dec 5;99(23):1782-92. • • • Barlow WE, White E, Ballard-Barbash R, Vacek PM, Titus-Ernstoff L, Carney PA, Tice JA, Buist DS, Geller BM, Rosenberg R, Yankaskas BC, Kerlikowske K.
J Natl Cancer Inst. 2006 Sep 6;98(17):1204-14. • • • Tice JA, Cummings SR, Smith-Bindman R, Ichikawa L, Barlow WE, Kerlikowske K.
Ann Intern Med. 2008 Mar 4;148(5):337-47. Summary for patients in: Ann Intern Med. 2008 Mar 4;148(5):I34.
• • • Tyrer J, Duffy SW, Cuzick J. 2004 Apr 15;23(7):1111-30. Erratum in: Stat Med. 2005 Jan 15;24(1):156.
• • Key articles citing this model: • • Colditz GA, Rosner B. Am J Epidemiol.
2000 Nov 15;152(10):950-64. • • • Rosner B, Colditz GA. J Natl Cancer Inst. 1996 Mar 20;88(6):359-64. • • Gail MH, Brinton LA, Byar DP, Corle DK, Green SB, Schairer C, Mulvihill JJ. J Natl Cancer Inst.
Berwick saga ps2. The sixth game in the Fire Emblem franchise, Tear Ring Saga, completely unrelated to Fire Emblem, is a strategy RPG created by Shouzou Kaga, the creator of Fire Emblem.
1989 Dec 20;81(24):1879-86. • • Key articles citing this model: • Models without Associated Websites • Pfeiffer RM, Park Y, Kreimer AR, et al. • Timmers JM, Verbeek AL, IntHout J, Pijnappel RM, Broeders MJ, den Heeten GJ. Sep 2013;23(9):2413-2419. • Dite GS, Mahmoodi M, Bickerstaffe A, et al. Breast Cancer Res Treat. Jun 2013;139(3):887-896.
• McCarthy AM, Armstrong K, Handorf E, et al. Breast Cancer Res Treat. Apr 2013;138(3):889-898. • Park B, Ma SH, Shin A, et al. • Husing A, Canzian F, Beckmann L, et al. Sep 2012;49(9):601-608. • Sueta A, Ito H, Kawase T, et al.
Breast Cancer Res Treat. Apr 2012;132(2):711-721. • Dai J, Hu Z, Jiang Y, Shen H, Dong J, Ma H.
Breast Cancer Res. • Darabi H, Czene K, Zhao W, Liu J, Hall P, Humphreys K. Breast Cancer Res. Feb 7 2012;14(1):R25. • Banegas MP, Gail MH, LaCroix A, et al. Breast Cancer Res Treat. Feb 2012;132(1):347-353.
• Dai J, Hu Z, Jiang Y, Shen H, Dong J, Ma H. Breast Cancer Res. Jan 23 2012;14(1):R17. • • McCowan C, Donnan PT, Dewar J, Thompson A, Fahey T. Br J Gen Pract. May 2011;61(586):e205-214.
• Crooke PS, Justenhoven C, Brauch H, et al. Cancer Epidemiol Biomarkers Prev.
Jul 2011;20(7):1502-1515. • van Zitteren M, van der Net JB, Kundu S, Freedman AN, van Duijn CM, Janssens AC. Cancer Epidemiol Biomarkers Prev. Jan 2011;20(1):9-22. • • Wacholder S, Hartge P, Prentice R, et al.
N Engl J Med. Mar 18 2010;362(11):986-993. • • Cook NR, Rosner BA, Hankinson SE, Colditz GA. Am J Epidemiol. Dec 1 2009;170(11):1422-1432. • Lee SM, Park JH, Park HJ. 2008 Sep-Oct;31(5):E40-6.
• Tice JA, Cummings SR, Smith-Bindman R, Ichikawa L, Barlow WE, Kerlikowske K. Ann Intern Med.
2008 Mar 4;148(5):337-47. Summary for patients in: Ann Intern Med. 2008 Mar 4;148(5):I34. • • Rosner B, Colditz GA, Iglehart JD, Hankinson SE. Breast Cancer Res. • • Chlebowski RT, Anderson GL, Lane DS, et al.